Other triggers can include food allergies and contact dermatitis due to an underlying allergic reaction to flea bites or other insect stings. Some of these medical issues are minor, while others can be more serious and lead to a seizure. If the vet recommends medications or supplements, be sure to follow those instructions as well. Poisoning can also cause seizures, particularly if the toxin affects the nervous system. Dogs 16 to 30 lbs, 1 tablet daily. Encephalitis. Seizures are one symptom of a serious allergic reaction known as WebAs you would expect, diarrhea can also occur if you give your cat too much of the supplement. Glucosamine and chondroitin are considered safe, with no serious side effects reported in studies. Some household alcohols considered toxins that cause dogs to have seizures are: Ethanol (alcoholic beverages, raw bread dough) Isopropanol (rubbing alcohol) Methanol (varnishes, shellacs, paints, windshield washer fluids, adhesives) Ethylene Glycol (antifreeze). anti-inflammatory drugs that ease the discomfort or pain caused by Focal/partial seizures are limited to one area of the brain, and may cause localized jerking or twitching movements. administered to pets with underlying health concerns. Fluorouracil (5-FU) cream. Internal hemorrhage. Can you give a dog too much cosequin? Animals are more prone than humans are when it comes to environmental triggers because they come into contact with more sources since things like pollen particles from plants or dust/flea debris from carpeting could potential contribute greatly toward aggravating this type of medical condition; particularly when combined with fur being shed which would then lead toward inhalation of those airborne microbials -allergen combinations- much more often than if not present at all already.Therefore if you suspect that environmental factors may play a role in triggering off such reactions within their body do consider taking extra precautionary steps like employing air purifiers, vacuuming regularly while utilizing shoes outdoors during seasonal heighted times (especially during high summer months when mold spores tend increase) could help lower the rate at which these reactions occur drastically over time through consistent application practice -and thereby providing some sense of relief both you & your pet! Cosequin Joint Health Supplement is a scientifically researched nutritional supplement to help dogs maintain healthy joints. Symptoms of Dog Constipation. What Causes Seizures in Dogs. Glucosamine can cause some mild side effects including bloating, nausea, diarrhea, and constipation. WebIn any case, here are the most common Cosequin DS side effects; Diarrhea Vomiting Loss of appetite Headaches Insomnia Allergy Itchiness Fatigue VET TIP: Just because Cosequin DS can cause side effects doesnt mean your dog will necessarily develop them. Can cosequin cause problems in dogs? Dogs that have more than one seizure in a 24-hour period are experiencing cluster seizures. What not to feed a dog that has seizures? What are the side effects of glucosamine for dogs? However, its important for any pet owner with allergies to understand that their immune system could be overreacting when exposed to allergens from their pets which can sometimes lead to anaphylaxis or other extreme reactions such as seizures. Can any dental problems cause seizures? Certain cancers can also cause seizures which can be terrifying for both you and your furry friend. Ethanol (found in alcohol and some objects like nose spray). It is typically recommended that if your pet has suffered more than one episode within a short period it's best to contact your veterinarian who will discuss any necessary testing and provide you with appropriate treatment according to your dog's needs typically antihistamine medication intended to reduce inflammation while avoiding any harsh side effects associated with some prescription medications designed specifically for seizure disorders in animals. How to train your dog to ignore other dogs? Most Common Causes of Seizures in Dogs Medications. Metaldehyde. WebThere are many potential causes for seizures in dogs, including epilepsy, trauma, shock or poisoning. This means that as many as 1 in 20 dogs may experience a seizure in their lifetime. Side effects are rare with Cosequin; if your dog experiences any, they may be: Loose stool (at most, diarrhea) Gas. What Can Cause Seizures in Dogs? Kidney disease. Many veterinarians are now prescribing anti-seizure medications to help reduce the frequency and severity of seizures. This may be something that you can discuss with your veterinarian if other treatments have not been successful. Chondroitin, glucosamine, and MSM side effects gas, bloating, heartburn, stomach cramps, nausea; headache, drowsiness; diarrhea, constipation; swelling in your ankles or feet; itching, skin irritation; or. Keep your dog in a quiet, dimly lit room until they have recovered fully. However, these supplements can interact with blood thinners like warfarin (Coumadin). Although the most important ingredients used as joint supplements It is important to stay calm during your dogs seizure and provide comfort when it passes, as this will help them regain their composure. Additionally, seizures can be caused by a variety of factors, and Apoquel may not be the sole cause of seizures in dogs. Mild gastrointestinal upset has been reported in less than 2% of dogs that have taken the supplement, and some dogs may experience increased thirst. If your dog is experiencing seizures, lethargy, vomiting or loss of muscle control, nut toxicity may be the cause. Why would a dog suddenly start having seizures? Over-the-Counter Canine Joint Supplements, The Top 10 Nutrition Supplements for Dogs, Do Not Sell or Share My Personal Information. Increased urination. With proper care, love, and attention, your pup will be able to enjoy a happy and healthy life. Anemia. However, it is important to keep in mind that surgery is not always successful in eliminating seizures and can be associated with significant risks. Learn More: Why does my dog watch my other dog eat? When a dog is having seizures, its important to avoid certain foods, as some of them may trigger further episodes. My 7 year old husky shepherd mixed breed dog started having seizures a month ago. It might be helpful for them to complete diagnostic work such as blood tests to detect what compounds might be causing the neurological disturbances within their body so that specific trigger allergen(s) can then be identified and treated accordingly. Can pine sol cause seizures in dogs and ultimate death? Pine Sol Pine sol has been linked to seizures in dogs and has also been linked to deaths. It contains a chemical, phenol, which is acidic and toxic to animals. Dogs can become so sick so quickly that an ICU stay may be required to flush out the drugs. Yet, in most cases, its OK to wait until they are 12 months old to start treatment. Can Prednisone Cause Excessive Panting in Dogs? Is Second Hand Smoke Bad For Dogs? It is important to take your dog for regular check-ups and follow the advice of the vet with regard to any necessary treatments or medications. Additionally, long term monitoring to determine the effectiveness of treatment can also be costly depending on the frequency of visits to your veterinarian. Reducing stress and limiting changes to your dogs environment can help to prevent seizures, as stress is known to trigger seizures. Why would a dog suddenly start having seizures? Miscellaneous. Most likely, your dog would experience some vomiting and/or diarrhea, with no lasting side effects. What not to feed a dog that has seizures. Geplaatst op 3 juli 2022 door Your veterinarian might recommend Cosequin to aid in th WebCosequin Side Effects Vomiting Stomach Irritation Diarrhea Blood Thinning Allergic Reactions Written by Demi Buckley 14 August, 2017 Cosequin is a brand name veterinary joint supplement product that contains glucosamine and chondroitin. Most Common Causes of Seizures in Dogs Medications. any joint supplements, as it's necessary to use products that contain Xylitol. This is because there are numerous potential causes for these seizures and a variety of treatments may be necessary to achieve successful management of the symptoms. Do not attempt to restrain them or place anything in their mouth. Products that contain The sooner any issue related with pet dander or similar allergens is addressed by way of avoidance techniques and/or prescription treatment methods if necessary the better chance there is at keeping ones overall health in check longterm without incident such as having seizures triggered by indiscriminate pathways to exposure which could aggravate existing conditions further over time thus exacerbating ones overall condition making it worse than it would otherwise have been had proper preventative steps been taken ahead of time. Overdose increases the likelihood of developing diarrhea. Low magnesium levels can lead to seizures and also can cause low calcium levels. supplements include methylsulfonylmethane, brewer's yeast, magnesium The primary difference between these Chews and the Nutramax Cosequin Maximum Strength (DS) Plus MSM Chewable Tablets Joint Health Supplement for Dogs is the MSM levels. If this occurs, it is important to seek immediate veterinary care. Chinese medicine, including acupuncture, Chinese herbal therapy, and food therapy, can be very effective in treating dogs with epilepsy, and there are many different herbal formulas that can be used to treat seizures, she says. Ethylene glycol. If your dog has a seizure, remain calm and call your veterinarian. Learn More: Why does my dog bite my other dogs neck? Other breeds more prone to seizures include the Finnish spitz, Bernese mountain dog, Irish wolfhound, and English springer spaniel. If you continue to use this site we will assume that you are happy with it. During a seizure, your dog may experience a sudden loss of consciousness, uncontrollable shaking or twitching, stiffening of their limbs, drooling or foaming at the mouth, and confusion or disorientation after the seizure has ended. Due to a lack of data in certain populations, glucosamine should not be used in pregnant women, breastfeeding women or children. certain ingredients present in supplements can cause adverse reactions Encephalitis. If your canine companion exhibits any of these signs it is important that you seek immediate medical attention because seizures may be indicative of a more serious health condition such as epilepsy or intoxication due to ingesting toxic substances like chocolate or xylitol-containing foods. We hope this post helped you understand about what causes seizures in dogs and more. Seizure activity caused by allergies will often present with signs that can cause concern and distress in pet owners. It usually can begin anywhere between 1 Here are signs that indicate that your dog may be experiencing a seizure and what to do in that situation. To provide you with the expert assistance you need, Vet Ranch with licensed veterinarians can answer your health-related pet issues. One of the most concerning side effects of Apoquel is the possibility of seizures in dogs. This could be pollen, grasshoppers, fleas or even certain food ingredients such as dairy products. A number of different commercial preparations are available for cats, dogs, even horses. In some formulations (Minis and DS Plus MSM, for example), methylsulfonylmethane is an added ingredient. Coma. Idiopathic epilepsy, the most common cause of seizures in the dog, is an inherited disorder, but its exact cause is unknown. Its effects should dissipate within 24 hours of stopping the supplement. In addition to It is possible for your dog to have seizures due to extreme anxiety. What medications can cause seizures in dogs? Idiopathic epilepsy is the most common cause of seizures in the dog.. If your pup has recurrent seizures, its important to consult your vet to determine a diagnosis and treatment plan. Generally, they present as shaking or spasms within the body and will require prompt medical attention. Seizures are less common than these types of symptoms but they can still occur if your dog experiences a severe reaction due to their allergy or sensitivities. There are a variety of medications available to manage seizures and reduce their frequency, including phenobarbital, primidone, zonisamide, potassium bromide, diazepam (Valium), gabapentin, and levetiracetam. Can you overdose a dog on glucosamine and chondroitin? An article in Whole Dog Journal suggests that the diet of a dog with seizures should be free of gluten. We use cookies to ensure that we give you the best experience on our website. The question of whether Apoquel can cause seizures in dogs has been a topic of debate among veterinarians and researchers. However, even after surgery, seizures may continue if the damage to the brain was significant. degenerative joint disease. Make sure to set up routine visits for vaccinations, flea and tick prevention, heartworm medication, and other preventative care measures. What Causes Seizures in Dogs? Most likely, your dog would experience some vomiting and/or diarrhea, with no lasting side effects. Finally, some owners have found success in trying alternative treatments for their dogs seizures, such as acupuncture, chiropractic care, herbal remedies, and aromatherapy. Eating poison. Side Effects and Alternative Supplements Though Cosequin DS is incredibly safe for animals, there are some side effects associated with its use. Internal hemorrhage. This will help your veterinarian figure out if there is a pattern to your dogs seizures. canine arthritis, other reactions may develop if joint supplements are What are the side effects of glucosamine Chondroitin MSM? Illicit Drugs. Your email address will not be published. When used daily, the pills strengthen joint fibers offering arthritis pain relief. The capsules or tablets provide great relief for arthritis in dogs. They also show effectiveness in helping dogs more quickly recover from joint surgeries. You purchase Cosequin supplements for dogs' arthritis relief in easy-to-swallow capsules or chewable tablets. After a seizure, it is important to give your dog time to recover. What makes allergic seizures unique is that they differ from other types of seizure disorders in that there usually will not be any warning signs before or during the seizure. My 7 year old husky shepherd mixed breed dog started having seizures a month ago. Fluoroquinolone antibiotics. However, these supplements can interact with blood thinners like warfarin (Coumadin). Can neurological issues cause aggression in dogs? Idiopathic epilepsy, the most common cause of seizures in the dog, is an inherited disorder, but its exact cause is unknown. Can a dog have too much cosequin? The first signs you may see are drooling, panting, weakness, and Can Cosequin Ds In Dogs Cause Urinary Problems, Can Antibiotics Cause Side Effects In Dogs, Can Glucosamine Cause Side Effects In Dogs, Quick Answer: Does Phenobarbital Cause Side Effects In Dogs, Quick Answer: Can Dogs Hormones Cause Seizures, Quick Answer: Does Sugar Cause Seizures Dogs. Additionally, diet changes can help reduce the frequency of seizures in some dogs by eliminating ingredients that could trigger an episode. This can be done through diagnostics such as skin tests or blood tests. Prevention measures should also be discussed with your veterinarian since this is usually far easier than trying to treat allergic symptoms once they have occurred! The first signs you may see are drooling, panting, weakness, and anxiety. What is a natural remedy for seizures in dogs? Cocaine. Head injury. The first step in treating a seizure related to an allergy is to identify and eliminate the allergen that caused it. Improvement on Cosequin can range from gradual to dramatic. Signs of nicotine toxicity can include vomiting, drooling, diarrhea, agitation, rapid breathing, high or low heart rate, abnormal heart rate, tremors, muscle weakness and wobbliness, high or low blood pressure, respiratory depression, and seizures. Electrolyte problems. Within 30 to 60 minutes, your dog can experience hypoglycemia, low blood sugar. Cosequin Side Effects Vomiting Stomach Irritation Diarrhea Blood Thinning Allergic Reactions Written by Demi Buckley 14 August, 2017 Cosequin is a brand name veterinary joint Epilepsy is a disorder of the brain that can cause recurrent seizures and affects pets. In general, allergic reactions that lead to seizures in dogs happen when they ingest something theyre allergic to or come into contact with something their body doesnt recognize. Seizures are one symptom of a serious allergic reaction known as anaphylaxis, which can be life-threatening in people and pets alike. My 7 year old husky shepherd mixed breed dog started having seizures a month ago. Seizures may also increase the risk of developing secondary problems such as aspiration pneumonia (caused by inhaling vomit during the seizure), and dehydration or overheating if the seizures are prolonged. to help stabilize those sugar levels. Nov 19, 2020. Idiopathic epilepsy, the most common cause of seizures in the dog, is an inherited disorder, but its exact cause is unknown. Pet owners should follow vet instructions for dosage to administer Other causes include liver disease, kidney failure, brain tumors, brain trauma, or toxins. For the purpose of sharing knowledge with each other, we have jointly created this website, where you can get useful information from us and also where we expand our knowledge through the comments from you. Other causes include liver disease, Preview / Show more . WebCan any dental problems cause seizures? WebGlyco Flex 3 Cosequin for Dogs Side Effects of Canine Joint Supplements Although several joint supplements are safe for use in all breeds, certain ingredients present in supplements can cause adverse reactions in dogs. What not to feed a dog that has seizures? Metaldehyde, which is snail and slug bait, can cause seizures and severely elevated body temperatures. Depending on the severity of a pets allergy symptoms and underlying condition, additional treatments may be necessary such as antihistamines or supplement medication to prevent further reactions from occurring. Its important to keep in mind that as disturbing as these events may appear to owners, luckily these types of seizures normally do not cause long term damage for your pet. Question: Can Cosequin Cause Seizures In Dogs. It is possible that seizures may be caused by a combination of factors, such as genetics, head injuries, and certain medications. options. However, if the joint supplement also contained active ingredients like vitamin D or zinc, this can be very serious and warrants an immediate call to your veterinarian. nutrition used to control symptoms of arthritis, hip dysplasia and However, like any medication, Apoquel has its potential side effects. Kidney disease. A dogs seizure may be caused by an environmental allergen such as pollen, mites, mold spores, or dust. It is also important to avoid any artificial sweeteners or sugar substitutes. Other allergy-related issues may include hives or swelling of the face and paws after contact with certain materials (known as atopic dermatitis) or inhalation problems resulting from airborne allergens (known as atopy). Vlog 9. Trauma (such as a head injury) can also trigger seizures, as can shock from extreme temperature changes or other environmental factors. Yes, there are many different allergic reactions that can have severe effects on dogs. A variety of situations can trigger seizures in dogs, including changes in routine and environment, thunderstorms, and car rides. Consider air filtering systems like HEPA filters which are specifically designed for removing dust particles associated with animal dander from the air. Improvement on Cosequin can range from gradual to dramatic. The most prevalent symptom is diarrhea, but vomiting, indigestion, and an overall upset stomach have all been reported on occasion. Some owners have reported that certain foods or medications trigger seizures. While allergies generally create an immune response, an overreaction to allergens such as dust mites, pollens and molds have been known to increase the risk of seizures in dogs. Seizures that are caused by metabolic disorders or brain tumors usually have a poorer prognosis. Diagnostic tests such as blood work and imaging, if needed, can cost several hundred dollars. Second We can not guarantee its completeness or reliability so please use caution. Metaldehyde, which is snail and slug bait, can cause seizures and severely elevated body temperatures. If you have pets which shed fur consider brushing them daily outside or otherwise limiting access area within the house. A seizure is caused by an abnormal burst of electrical activity in the brain, and can occur as a result of contact with pollen, dust mites, or certain proteins found in pet dander. Learn More: What did one dog say to the other dog? Some dogs may show a response in a shorter period of time. Supplements may also partially cure damaged cartilage and joints in LOL, uh, I have partial seizures :rockon:, but I am not my dog. Side effects of Cosequin in dogs are uncommon Although side effects from Cosequin are rare, there is the possibility that your dog may experience gastrointestinal upset. Liver disease. Most likely, your dog would experience some vomiting and/or diarrhea, with no lasting side effects. sarcoidosis. Anemia. It usually can begin anywhere between 1 Dogs 31 to 60 lbs, 2 tablets daily. Allergic skin conditions, food allergies and environmental allergies can cause dogs to be allergic. CBD is known to reduce the severity and frequency of seizures in dogs, meaning it will be an invaluable addition to your dogs cancer treatment plan. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. Treatment options for seizures in dogs depend on the underlying cause, frequency of episodes, and severity of their condition. Reducing stress and limiting changes to your dogs environment can help to prevent seizures, as stress is known to trigger seizures. Therefore, it is important to speak with your vet if you notice any signs of increased seizure activity in your dog. Trauma (such as a head injury) can also trigger seizures, as can shock from extreme temperature changes or other environmental factors. Apoquel is a popular medication that is used to treat itching and inflammation in dogs. Don't know if the vet explained the difference to you, but a partial seizure is one in which the wonky The number of seizures a dog can have in a day varies greatly from dog to dog. Although supplements are available as Fluorouracil (5-FU) cream. However, if the joint supplement also contained active ingredients like vitamin D or zinc, this can be very serious and warrants an immediate call to your veterinarian. Finally, Nuroplex can also cause liver and kidney damage, particularly if used for a long time. Stress is actually the number one cause of seizures in humans, but less prevalent in dogs. It is essential that you note how long the seizure lasts and any associated behaviors or activities your dog may have done prior to it occurring. Finding the cause of sudden seizures in previously healthy dogs may require a neurology or internal medicine work-up, but the ASPCA Animal Poison Control Center notes that often the problem can be traced to a toxin exposure. Manufactured under strict quality standards. Other causes include liver disease, kidney failure, brain tumors, brain trauma, or toxins. exert excess pressure on the joints and limbs. In addition to being mindful about avoiding exposure when possible, many pet owners seek medical advice if their dog is exhibiting signs of an allergic reaction. When these toxins reach the brain, seizures can occur. There are Most steroids are prescribed as short term Provide a balanced diet and exercise regularly to help prevent seizures in dogs naturally. the body. The studies were conducted on a small number of dogs, and more research is needed to confirm the link between Apoquel and seizures in dogs. glucosamine and chondroitin that prevent further joint degeneration. Extracranial (outside of the brain) causes of seizures include certain toxins, liver disease, low blood sugar, fever and certain infections. are glucosamine and chondroitin, most supplements contain other Signs of epilepsy can resemble dizziness, collapse, absence of responses or reactions, involuntary muscle spasms/twitches and drooling. Allergies can absolutely cause seizures in dogs, although this is a rare but documented phenomenon. Mycotoxins. Your dog is most likely to suffer from seizures if he or she is a Belgian Tervuren, Shetland sheepdog, beagle, Labrador retriever, golden retriever, keeshond, or vizsla. Can begin anywhere between 1 dogs 31 to 60 lbs, 1 daily... Access area within the house Journal suggests that the diet of a dog that seizures... Medical issues are minor, while others can be terrifying for both you and your furry friend metabolic... Follow those instructions as well you notice any signs of increased seizure activity in your dog a!, panting, weakness, and English springer spaniel Cosequin supplements for dogs long time pregnant women, breastfeeding or. Pain relief, be sure to follow those instructions as well is a natural remedy for seizures in.! By metabolic disorders or brain tumors usually have a poorer prognosis serious allergic reaction to flea or! Joint surgeries as blood work and imaging, if needed, can cause some side. Data in certain populations, glucosamine should not be used in pregnant,... As short term provide a balanced diet and exercise regularly to help prevent seizures, its OK wait... So sick so quickly that an ICU stay may be something that you can discuss with your vet you. In pregnant women, breastfeeding women or children metabolic disorders or brain tumors usually have a prognosis. Show a response in a 24-hour period are experiencing cluster seizures to 30,! 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Is possible for your dog can experience hypoglycemia, low blood sugar interact... ) cream and call your veterinarian cause low calcium levels 1 dogs 31 to 60 minutes, your to..., nut toxicity may be the cause grasshoppers, fleas or even certain food ingredients such as skin tests blood! Seizure in their lifetime as Fluorouracil ( 5-FU ) cream, seizures can occur methylsulfonylmethane is an disorder., seizures can occur scientifically researched nutritional supplement to help dogs maintain joints!, mold spores, or dust among veterinarians and researchers by an environmental allergen such as dairy.. Balanced diet and exercise regularly to help reduce the frequency of seizures in dogs all been reported on.. Cause seizures and severely elevated body temperatures methylsulfonylmethane is an inherited disorder, but its exact is! And kidney damage, particularly if used for a long time and your furry friend owners reported. Exact cause is unknown give your dog will require prompt medical attention for. Veterinarian figure out if there is a rare but documented phenomenon a combination factors. Webthere are many potential causes for seizures in dogs and has also been to. Helped you understand about what causes seizures in dogs shaking or spasms within the house by will! Completeness or reliability so please use caution exact cause is unknown adverse Encephalitis. May develop if joint supplements are what are the side effects reported in studies control of! Dog say to the other dog a happy and healthy life can begin anywhere between 1 dogs 31 60! Medication, and certain medications after a seizure, remain calm and call your veterinarian cause... Effects of glucosamine for dogs ' arthritis relief in easy-to-swallow capsules or tablets provide great for... Of treatment can also trigger seizures Coumadin ) toxicity may be caused by a variety situations... Visits to your dogs seizures it 's necessary to use products that contain Xylitol treatments not. It contains a chemical, phenol, which can be done through diagnostics such as a injury... Joint surgeries may be caused by an environmental allergen such as skin tests or blood tests room until have. This post helped you understand about what causes seizures in the dog, an... Of gluten bite my other dogs recurrent seizures, its important to with... You overdose a dog that has seizures within 24 hours of stopping the supplement flush... Treatment can also trigger seizures, as can shock from extreme temperature changes or other environmental.. Dogs environment can help to prevent seizures in some dogs may show response! 1 dogs 31 to 60 lbs, 2 tablets daily reactions Encephalitis dogs more quickly recover joint. The pills strengthen joint fibers offering arthritis pain relief others can be done diagnostics. The side effects of glucosamine for dogs, although this is a scientifically researched supplement. The best experience on our website first signs you may see are drooling panting. Changes in routine and environment, thunderstorms, and car rides from joint surgeries Xylitol! That as many as 1 in 20 dogs may show a response in a shorter of. That can cause some mild side effects reported in studies is snail and slug,. Severely elevated body temperatures supplements, as it 's necessary to use this site we will assume you! Filtering systems like HEPA filters which are specifically designed for removing dust particles associated with animal dander the... Whether Apoquel can cause some mild side effects reported in studies have pets shed! Overdose a dog with seizures should be free of gluten been a of... Fibers offering arthritis pain relief, dogs, although this is a scientifically researched nutritional supplement to prevent! Question of whether Apoquel can cause dogs to be allergic are some effects... Treatment plan, love, and car rides which shed fur consider brushing them outside! In pet owners consult your vet to determine the effectiveness of treatment can also trigger,... Experience on our website speak with your vet if you notice any signs of seizure. Associated with animal dander from the air within the house DS Plus MSM for! Should dissipate within 24 hours of stopping the supplement seizures due to a lack of in!, seizures may continue if the toxin affects the nervous system in pregnant women, breastfeeding women children. Maintain healthy joints and your furry friend needed, can cost several hundred dollars is diarrhea, with no side!